Sodium Starch Glycolate
Nanjing Muzhi Biotechnology Co., Ltd.
Email: xw79835@gmail.com
Phone: 025-58186679
Address: Room 204, Block C, Hatching Building, No. 99, Tuanjie Road, Jiangpu Street, Pukou District, Nanjing, Jiangsu Province
Sodium starch glycolate has good water absorption and swelling properties and is also compressible. It can improve the tablet's formability and increase the tablet's hardness without affecting its disintegration. It can accelerate the disintegration of tablets, greatly improving the drug's solubility and bioavailability. Sodium starch glycolate with relatively high viscosity can be used as a sustained-release material. It is mostly used in psychotropic drugs, antipyretic analgesics, and digestive system drugs. Sodium starch glycolate achieves rapid and significant swelling through rapid water absorption, thereby playing a disintegrating role. It is suitable for direct tableting or wet granulation processes. The commonly used range in the formulation is 2-8%. Although the disintegration of many disintegrants is affected by hydrophobic excipients (such as lubricants), sodium starch glycolate is less affected by them. Increasing the tableting pressure also seems to not affect on the disintegration time. Sodium starch glycolate has also been studied as a suspending agent.
Nanjing Muzhi Biotechnology Co., Ltd.
Email: xw79835@gmail.com
Phone: 025-58186679
Address: Room 204, Block C, Hatching Building, No. 99, Tuanjie Road, Jiangpu Street, Pukou District, Nanjing, Jiangsu Province
Sodium starch glycolate has good water absorption and swelling properties and is also compressible. It can improve the tablet's formability and increase the tablet's hardness without affecting its disintegration. It can accelerate the disintegration of tablets, greatly improving the drug's solubility and bioavailability. Sodium starch glycolate with relatively high viscosity can be used as a sustained-release material. It is mostly used in psychotropic drugs, antipyretic analgesics, and digestive system drugs. Sodium starch glycolate achieves rapid and significant swelling through rapid water absorption, thereby playing a disintegrating role. It is suitable for direct tableting or wet granulation processes. The commonly used range in the formulation is 2-8%. Although the disintegration of many disintegrants is affected by hydrophobic excipients (such as lubricants), sodium starch glycolate is less affected by them. Increasing the tableting pressure also seems to not affect on the disintegration time. Sodium starch glycolate has also been studied as a suspending agent.
